Human inherited CCR2 deficiency underlies progressive polycystic lung disease.
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Cell. 2024 Jan 18;187(2):390-408.e23. doi: 10.1016/j.cell.2023.11.036. Epub 2023 Dec 28.
Cell. 2024.
PMID: 38157855
Free PMC article.
Blood myeloid and lymphoid subsets and interferon (IFN)-gamma- and granulocyte-macrophage colony-stimulating factor (GM-CSF)-mediated immunity are unaffected. CCR2-deficient monocytes and alveolar macrophage-like cells have normal gene expression profiles and functions. .. …
Blood myeloid and lymphoid subsets and interferon (IFN)-gamma- and granulocyte-macrophage colony-stimulating factor (GM-CSF)-mediated …